c-abl,proto-oncogene proteins meaning in Chinese

《英文msh词典》c-abl,Proto-Oncogene Proteins
[入口词] c-abl,Proto-Oncogene Proteins
[主题词] Proto-Oncogene Proteins c-abl
[英文释义] Non-receptor tyrosine kinases encoded by the c-abl gene. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal hematopoiesis especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted,releasing the kinase from negative regulation.